Endotheliopathy and Platelet Dysfunction as Hallmarks of Fatal Lassa Fever

Lassa fever (LF) causes multisystem disease and has a fatality rate <70%. Severe cases exhibit abnormal coagulation, endothelial barrier disruption, and dysfunctional platelet aggregation but the underlying mechanisms remain poorly understood. In Sierra Leone during 2015–2018, we assessed LF pati...

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Detalles Bibliográficos
Autores principales: Horton, Lucy E., Cross, Robert W., Hartnett, Jessica N., Engel, Emily J., Sakabe, Saori, Goba, Augustine, Momoh, Mambu, Sandi, John Demby, Geisbert, Thomas W., Garry, Robert F., Schieffelin, John S., Grant, Donald S., Sullivan, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588510/
https://www.ncbi.nlm.nih.gov/pubmed/33079033
http://dx.doi.org/10.3201/eid2611.191694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588510/
https://www.ncbi.nlm.nih.gov/pubmed/33079033
http://dx.doi.org/10.3201/eid2611.191694

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