Structural insight into FANCI–FANCD2 monoubiquitination

The Fanconi anemia (FA) pathway coordinates a faithful repair mechanism for DNA damage that blocks DNA replication, such as interstrand cross-links. A key step in the FA pathway is the conjugation of ubiquitin on to FANCD2 and FANCI, which is facilitated by a large E3 ubiquitin ligase complex called...

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Detalles Bibliográficos
Autores principales: Li, Landing, Tan, Winnie, Deans, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588663/
https://www.ncbi.nlm.nih.gov/pubmed/32725171
http://dx.doi.org/10.1042/EBC20200001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588663/
https://www.ncbi.nlm.nih.gov/pubmed/32725171
http://dx.doi.org/10.1042/EBC20200001

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