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Base excision repair and its implications to cancer therapy

Base excision repair (BER) has evolved to preserve the integrity of DNA following cellular oxidative stress and in response to exogenous insults. The pathway is a coordinated, sequential process involving 30 proteins or more in which single strand breaks are generated as intermediates during the rep...

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Detalles Bibliográficos
Autores principales: Grundy, Gabrielle J., Parsons, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588666/
https://www.ncbi.nlm.nih.gov/pubmed/32648895
http://dx.doi.org/10.1042/EBC20200013