Cargando…

Direct ENIT: An easy and reliable tool for gRNA efficacy verification by tracking induced chromosomal translocation

CRISPR/Cas systems (Clustered regularly interspaced palindromic repeats / CRISPR-associated) are rapidly becoming a commonplace and popular tool for gene editing in research and clinical contexts. However, the quality of CRISPR/Cas experiments depends heavily on the guide RNA (gRNA) design; therefor...

Descripción completa

Detalles Bibliográficos
Autores principales: Lomov, Nikolai A., Viushkov, Vladimir S., Zamalutdinov, Aleksei V., Sboeva, Maria D., Rubtsov, Mikhail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588861/
https://www.ncbi.nlm.nih.gov/pubmed/33134100
http://dx.doi.org/10.1016/j.mex.2020.101104