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Direct ENIT: An easy and reliable tool for gRNA efficacy verification by tracking induced chromosomal translocation
CRISPR/Cas systems (Clustered regularly interspaced palindromic repeats / CRISPR-associated) are rapidly becoming a commonplace and popular tool for gene editing in research and clinical contexts. However, the quality of CRISPR/Cas experiments depends heavily on the guide RNA (gRNA) design; therefor...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588861/ https://www.ncbi.nlm.nih.gov/pubmed/33134100 http://dx.doi.org/10.1016/j.mex.2020.101104 |