Fatty Acid Synthase Is a Key Enabler for Endocrine Resistance in Heregulin-Overexpressing Luminal B-Like Breast Cancer

HER2 transactivation by the HER3 ligand heregulin (HRG) promotes an endocrine-resistant phenotype in the estrogen receptor-positive (ER+) luminal-B subtype of breast cancer. The underlying biological mechanisms that link them are, however, incompletely understood. Here, we evaluated the putative rol...

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Detalles Bibliográficos
Autores principales: Menendez, Javier A., Mehmi, Inderjit, Papadimitropoulou, Adriana, Vander Steen, Travis, Cuyàs, Elisabet, Verdura, Sara, Espinoza, Ingrid, Vellon, Luciano, Atlas, Ella, Lupu, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588883/
https://www.ncbi.nlm.nih.gov/pubmed/33081219
http://dx.doi.org/10.3390/ijms21207661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588883/
https://www.ncbi.nlm.nih.gov/pubmed/33081219
http://dx.doi.org/10.3390/ijms21207661

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