Cutting the Brakes on Ras—Cytoplasmic GAPs as Targets of Inactivation in Cancer

SIMPLE SUMMARY: GTPase-Activating Proteins (RasGAPs) are a group of structurally related proteins with a fundamental role in controlling the activity of Ras in normal and cancer cells. In particular, loss of function of RasGAPs may contribute to aberrant Ras activation in cancer. Here we review the...

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Detalles Bibliográficos
Autores principales: Bellazzo, Arianna, Collavin, Licio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588890/
https://www.ncbi.nlm.nih.gov/pubmed/33096593
http://dx.doi.org/10.3390/cancers12103066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588890/
https://www.ncbi.nlm.nih.gov/pubmed/33096593
http://dx.doi.org/10.3390/cancers12103066

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