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Cutting the Brakes on Ras—Cytoplasmic GAPs as Targets of Inactivation in Cancer
SIMPLE SUMMARY: GTPase-Activating Proteins (RasGAPs) are a group of structurally related proteins with a fundamental role in controlling the activity of Ras in normal and cancer cells. In particular, loss of function of RasGAPs may contribute to aberrant Ras activation in cancer. Here we review the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588890/ https://www.ncbi.nlm.nih.gov/pubmed/33096593 http://dx.doi.org/10.3390/cancers12103066 |