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Selective Blockade of TNFR1 Improves Clinical Disease and Bronchoconstriction in Experimental RSV Infection

Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis in infants and young children. Although some clinical studies have speculated that tumor necrosis factor (TNF)-α is a major contributor of RSV-mediated airway disease, experimental evidence remains unclear or conflicting. TNF-α...

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Detalles Bibliográficos
Autores principales: Morris, Dorothea R., Ansar, Maria, Ivanciuc, Teodora, Qu, Yue, Casola, Antonella, Garofalo, Roberto P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588931/
https://www.ncbi.nlm.nih.gov/pubmed/33080861
http://dx.doi.org/10.3390/v12101176