Chrysoeriol Prevents TNFα-Induced CYP19 Gene Expression via EGR-1 Downregulation in MCF7 Breast Cancer Cells

Estrogen overproduction is closely associated with the development of estrogen receptor-positive breast cancer. Aromatase, encoded by the cytochrome P450 19 (CYP19) gene, regulates estrogen biosynthesis. This study aimed to identify active flavones that inhibit CYP19 expression and to explore the un...

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Detalles Bibliográficos
Autores principales: Min, Dong Yeong, Jung, Euitaek, Ahn, Sung Shin, Lee, Young Han, Lim, Yoongho, Shin, Soon Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588959/
https://www.ncbi.nlm.nih.gov/pubmed/33053908
http://dx.doi.org/10.3390/ijms21207523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588959/
https://www.ncbi.nlm.nih.gov/pubmed/33053908
http://dx.doi.org/10.3390/ijms21207523

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