Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity

Our previous studies identified that retinal endothelial damage caused by hyperglycemia or nucleoside diphosphate kinase-B (NDPK-B) deficiency is linked to elevation of angiopoietin-2 (Ang-2) and the activation of the hexosamine biosynthesis pathway (HBP). Herein, we investigated how NDPK-B is invol...

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Detalles Bibliográficos
Autores principales: Chatterjee, Anupriya, Eshwaran, Rachana, Poschet, Gernot, Lomada, Santosh, Halawa, Mahmoud, Wilhelm, Kerstin, Schmidt, Martina, Hammes, Hans-Peter, Wieland, Thomas, Feng, Yuxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588982/
https://www.ncbi.nlm.nih.gov/pubmed/33086728
http://dx.doi.org/10.3390/cells9102324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588982/
https://www.ncbi.nlm.nih.gov/pubmed/33086728
http://dx.doi.org/10.3390/cells9102324

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