Thermodynamic Insights by Microscale Thermophoresis into Translesion DNA Synthesis Catalyzed by DNA Polymerases Across a Lesion of Antitumor Platinum–Acridine Complex

Translesion synthesis (TLS) through DNA adducts of antitumor platinum complexes has been an interesting aspect of DNA synthesis in cells treated with these metal-based drugs because of its correlation to drug sensitivity. We utilized model systems employing a DNA lesion derived from a site-specific...

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Detalles Bibliográficos
Autores principales: Hreusova, Monika, Novakova, Olga, Brabec, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589001/
https://www.ncbi.nlm.nih.gov/pubmed/33096927
http://dx.doi.org/10.3390/ijms21207806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589001/
https://www.ncbi.nlm.nih.gov/pubmed/33096927
http://dx.doi.org/10.3390/ijms21207806

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