Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R)

Sigma-1 receptor (S1R) is a promising molecular target for the development of novel effective therapies against neurodegenerative diseases. To speed up the discovery of new S1R modulators, herein we report the development of a reliable in silico protocol suitable to predict the affinity of small mol...

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Detalles Bibliográficos
Autores principales: Rossino, Giacomo, Rui, Marta, Pozzetti, Luca, Schepmann, Dirk, Wünsch, Bernhard, Zampieri, Daniele, Pellavio, Giorgia, Laforenza, Umberto, Rinaldi, Silvia, Colombo, Giorgio, Morelli, Laura, Linciano, Pasquale, Rossi, Daniela, Collina, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589021/
https://www.ncbi.nlm.nih.gov/pubmed/33081037
http://dx.doi.org/10.3390/ijms21207708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589021/
https://www.ncbi.nlm.nih.gov/pubmed/33081037
http://dx.doi.org/10.3390/ijms21207708

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