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Microglia in Prion Diseases: Angels or Demons?

Prion diseases are rare transmissible neurodegenerative disorders caused by the accumulation of a misfolded isoform (PrP(Sc)) of the cellular prion protein (PrP(C)) in the central nervous system (CNS). Neuropathological hallmarks of prion diseases are neuronal loss, astrogliosis, and enhanced microg...

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Detalles Bibliográficos
Autores principales: Peggion, Caterina, Stella, Roberto, Lorenzon, Paolo, Spisni, Enzo, Bertoli, Alessandro, Massimino, Maria Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589037/
https://www.ncbi.nlm.nih.gov/pubmed/33092220
http://dx.doi.org/10.3390/ijms21207765