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Microglia in Prion Diseases: Angels or Demons?
Prion diseases are rare transmissible neurodegenerative disorders caused by the accumulation of a misfolded isoform (PrP(Sc)) of the cellular prion protein (PrP(C)) in the central nervous system (CNS). Neuropathological hallmarks of prion diseases are neuronal loss, astrogliosis, and enhanced microg...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589037/ https://www.ncbi.nlm.nih.gov/pubmed/33092220 http://dx.doi.org/10.3390/ijms21207765 |