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Single-Dose Cisplatin Pre-Treatment Enhances Efficacy of ROBO1-Targeted Radioimmunotherapy

We previously reported that radioimmunotherapy (RIT) using (90)Y-labeled anti-ROBO1 IgG ((90)Y-B5209B) achieved significant anti-tumor effects against small-cell lung cancer (SCLC) xenografts. However, subsequent tumor regrowth suggested the necessity for more effective therapy. Here, we evaluated t...

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Detalles Bibliográficos
Autores principales: Fujiwara, Kentaro, Koyama, Keitaro, Tsuji, Atsushi B., Iwanari, Hiroko, Kusano-Arai, Osamu, Higashi, Tatsuya, Momose, Toshimitsu, Hamakubo, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589062/
https://www.ncbi.nlm.nih.gov/pubmed/33086574
http://dx.doi.org/10.3390/ijms21207728