De Novo T790M Mutation in an L858R Epidermal Growth Factor Receptor Mutant-Associated Lung Adenocarcinoma

SIMPLE SUMMARY: Lung adenocarcinomas caused by (L858R) somatic mutation in the epidermal growth factor receptor (EGFR) show good therapeutic response to tyrosine kinase inhibitors. These tumors develop resistance to therapy mainly after acquired T790M mutation. However, whether the T790M mutation oc...

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Detalles Bibliográficos
Autores principales: Fujiwara, Takumi, Kobayashi, Tetsu, Yasuma, Taro, D’Alessandro-Gabazza, Corina N., Toda, Masaaki, Fujimoto, Hajime, Fujiwara, Kentaro, Takeshita, Atsuro, Nishihama, Kota, Okano, Tomohito, D’Alessandro, Valeria Fridman, Takei, Yoshiyuki, Hataji, Osamu, Gabazza, Esteban C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589092/
https://www.ncbi.nlm.nih.gov/pubmed/33096790
http://dx.doi.org/10.3390/cancers12103074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589092/
https://www.ncbi.nlm.nih.gov/pubmed/33096790
http://dx.doi.org/10.3390/cancers12103074

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