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Polysulfide and Hydrogen Sulfide Ameliorate Cisplatin-Induced Nephrotoxicity and Renal Inflammation through Persulfidating STAT3 and IKKβ

Cisplatin, a widely used chemotherapy for the treatment of various tumors, is clinically limited due to its extensive nephrotoxicity. Inflammatory response in tubular cells is a driving force for cisplatin-induced nephrotoxicity. The plant-derived agents are widely used to relieve cisplatin-induced...

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Detalles Bibliográficos
Autores principales: Sun, Hai-Jian, Leng, Bin, Wu, Zhi-Yuan, Bian, Jin-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589167/
https://www.ncbi.nlm.nih.gov/pubmed/33096924
http://dx.doi.org/10.3390/ijms21207805