High Adenosine Extracellular Levels Induce Glioblastoma Aggressive Traits Modulating the Mesenchymal Stromal Cell Secretome

Glioblastoma is an aggressive, fast-growing brain tumor influenced by the composition of the tumor microenvironment (TME) in which mesenchymal stromal cell (MSCs) play a pivotal role. Adenosine (ADO), a purinergic signal molecule, can reach up to high micromolar concentrations in TME. The activity o...

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Detalles Bibliográficos
Autores principales: Pietrobono, Deborah, Giacomelli, Chiara, Marchetti, Laura, Martini, Claudia, Trincavelli, Maria Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589183/
https://www.ncbi.nlm.nih.gov/pubmed/33081024
http://dx.doi.org/10.3390/ijms21207706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589183/
https://www.ncbi.nlm.nih.gov/pubmed/33081024
http://dx.doi.org/10.3390/ijms21207706

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