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Alpha-B-Crystallin Effect on Mature Amyloid Fibrils: Different Degradation Mechanisms and Changes in Cytotoxicity

Given the ability of molecular chaperones and chaperone-like proteins to inhibit the formation of pathological amyloid fibrils, the chaperone-based therapy of amyloidosis has recently been proposed. However, since these diseases are often diagnosed at the stages when a large amount of amyloids is al...

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Detalles Bibliográficos
Autores principales: Stepanenko, Olga V., Sulatsky, M. I., Mikhailova, E. V., Stepanenko, Olesya V., Povarova, O. I., Kuznetsova, I. M., Turoverov, K. K., Sulatskaya, A. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589196/
https://www.ncbi.nlm.nih.gov/pubmed/33081200
http://dx.doi.org/10.3390/ijms21207659