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Identification of Putative Non-Substrate-Based XT-I Inhibitors by Natural Product Library Screening
Fibroproliferative diseases are characterized by excessive accumulation of extracellular matrix (ECM) components leading to organ dysfunction. This process is characterized by an increase in myofibroblast content and enzyme activity of xylosyltransferase-I (XT-I), the initial enzyme in proteoglycan...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589200/ https://www.ncbi.nlm.nih.gov/pubmed/33096778 http://dx.doi.org/10.3390/biom10101467 |