Maternal sildenafil impairs the cardiovascular adaptations to chronic hypoxaemia in fetal sheep

KEY POINTS: Fetal growth restriction induces a haemodynamic response that aims to maintain blood flow to vital organs such as the brain, in the face of chronic hypoxaemia. Maternal sildenafil treatment impairs the hypoxaemia‐driven haemodynamic response and potentially compromises fetal development....

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Detalles Bibliográficos
Autores principales: Inocencio, Ishmael M., Polglase, Graeme R., Nitsos, Ilias, Miller, Suzanne L., Allison, Beth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Placenta, Pregnancy and Perinatal Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589206/
https://www.ncbi.nlm.nih.gov/pubmed/32754905
http://dx.doi.org/10.1113/JP279248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589206/
https://www.ncbi.nlm.nih.gov/pubmed/32754905
http://dx.doi.org/10.1113/JP279248

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