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Hypoxic Melanoma Cells Deliver microRNAs to Dendritic Cells and Cytotoxic T Lymphocytes through Connexin-43 Channels

Alterations in microRNA (miRNA) profiles, induced by tumor microenvironment stressors, like hypoxia, allow cancer cells to acquire immune-resistance phenotypes. Indeed, hypoxia-induced miRNAs have been implicated in cancer progression through numerous cancer cell non-autonomous mechanisms, including...

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Detalles Bibliográficos
Autores principales: Tittarelli, Andrés, Navarrete, Mariela, Lizana, Marcelo, Hofmann-Vega, Francisca, Salazar-Onfray, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589225/
https://www.ncbi.nlm.nih.gov/pubmed/33066331
http://dx.doi.org/10.3390/ijms21207567