Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel

KEY POINTS: 25‐Hydroxyvitamin D (25OHD) is a partial agonist of TRPV1 whereby 25OHD can weakly activate TRPV1 yet antagonize the stimulatory effects of the full TRPV1 agonists capsaicin and oleoyl dopamine. 25OHD binds to TRPV1 within the same vanilloid binding pocket as capsaicin. 25OHD inhibits th...

Descripción completa

Detalles Bibliográficos
Autores principales: Long, Wentong, Fatehi, Mohammad, Soni, Shubham, Panigrahi, Rashmi, Philippaert, Koenraad, Yu, Yi, Kelly, Rees, Boonen, Brett, Barr, Amy, Golec, Dominic, Campbell, Scott A., Ondrusova, Katarina, Hubert, Matt, Baldwin, Troy, Lemieux, M. Joanne, Light, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Molecular and Cellular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589233/
https://www.ncbi.nlm.nih.gov/pubmed/32721035
http://dx.doi.org/10.1113/JP279961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589233/
https://www.ncbi.nlm.nih.gov/pubmed/32721035
http://dx.doi.org/10.1113/JP279961

Ejemplares similares