Activity‐Directed Synthesis: A Flexible Approach for Lead Generation

Activity‐directed synthesis (ADS) is a structure‐blind, functional‐driven molecular discovery approach. In this Concept, four case studies highlight the general applicability of ADS and showcase its flexibility to support different medicinal chemistry strategies. ADS deliberately harnesses reactions...

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Detalles Bibliográficos
Autores principales: Karageorgis, George, Liver, Samuel, Nelson, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Concepts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589241/
https://www.ncbi.nlm.nih.gov/pubmed/32734671
http://dx.doi.org/10.1002/cmdc.202000524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589241/
https://www.ncbi.nlm.nih.gov/pubmed/32734671
http://dx.doi.org/10.1002/cmdc.202000524

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