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Activity‐Directed Synthesis: A Flexible Approach for Lead Generation

Activity‐directed synthesis (ADS) is a structure‐blind, functional‐driven molecular discovery approach. In this Concept, four case studies highlight the general applicability of ADS and showcase its flexibility to support different medicinal chemistry strategies. ADS deliberately harnesses reactions...

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Detalles Bibliográficos
Autores principales:	Karageorgis, George, Liver, Samuel, Nelson, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Concepts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589241/ https://www.ncbi.nlm.nih.gov/pubmed/32734671 http://dx.doi.org/10.1002/cmdc.202000524

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