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Healthy Donors Harbor Memory T Cell Responses to RAS Neo-Antigens

SIMPLE SUMMARY: Memory T cells from healthy individuals respond to stimulation with peptides derived from cancer-specific RAS mutations, thus suggesting that healthy individuals have been challenged with RAS mutations earlier in life. ABSTRACT: The RAS mutations are the most frequently occurring som...

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Detalles Bibliográficos
Autores principales: Holmström, Morten Orebo, Andersen, Mads Hald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589254/
https://www.ncbi.nlm.nih.gov/pubmed/33086698
http://dx.doi.org/10.3390/cancers12103045