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Development of a Novel SPR Assay to Study CXCR4–Ligand Interactions

G protein-coupled receptors (GPCRs) are involved in a plethora of different diseases. Consequently, these proteins are considered as an important class of drug targets. Measuring detailed kinetic information on these types of proteins has been challenging. Surface plasmon resonance (SPR) can provide...

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Detalles Bibliográficos
Autores principales: Boonen, Arnaud, Singh, Abhimanyu K., Hout, Anneleen Van, Das, Kalyan, Loy, Tom Van, Noppen, Sam, Schols, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589327/
https://www.ncbi.nlm.nih.gov/pubmed/33096938
http://dx.doi.org/10.3390/bios10100150