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Y-27632 Induces Neurite Outgrowth by Activating the NOX1-Mediated AKT and PAK1 Phosphorylation Cascades in PC12 Cells

Y-27632 is known as a selective Rho-associated coiled coil-forming kinase (ROCK) inhibitor. Y-27632 has been shown to induce neurite outgrowth in several neuronal cells. However, the precise molecular mechanisms linking neurite outgrowth to Y-27632 are not completely understood. In this study, we ex...

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Detalles Bibliográficos
Autores principales: Park, So Yeong, An, Jeong Mi, Seo, Jeong Taeg, Seo, Su Ryeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589331/
https://www.ncbi.nlm.nih.gov/pubmed/33081375
http://dx.doi.org/10.3390/ijms21207679