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N (6)‐Isopentenyladenosine in RNA Determines the Cleavage Site of Endonuclease Deoxyribozymes

RNA‐cleaving deoxyribozymes can serve as selective sensors and catalysts to examine the modification state of RNA. However, site‐specific endonuclease deoxyribozymes that selectively cleave post‐transcriptionally modified RNA are extremely rare and their specificity over unmodified RNA is low. We re...

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Detalles Bibliográficos
Autores principales: Liaqat, Anam, Stiller, Carina, Michel, Manuela, Sednev, Maksim V., Höbartner, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589339/
https://www.ncbi.nlm.nih.gov/pubmed/32681686
http://dx.doi.org/10.1002/anie.202006218