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An α‐Cyclopropanation of Carbonyl Derivatives by Oxidative Umpolung

The reactivity of iodine(III) reagents towards nucleophiles is often associated with umpolung and cationic mechanisms. Herein, we report a general process converting a range of ketone derivatives into α‐cyclopropanated ketones by oxidative umpolung. Mechanistic investigation and careful characteriza...

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Detalles Bibliográficos
Autores principales: Bauer, Adriano, Di Mauro, Giovanni, Li, Jing, Maulide, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589340/
https://www.ncbi.nlm.nih.gov/pubmed/32808419
http://dx.doi.org/10.1002/anie.202007439