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Doxorubicin-Induced Translocation of mtDNA into the Nuclear Genome of Human Lymphocytes Detected Using a Molecular-Cytogenetic Approach

Translocation of mtDNA in the nuclear genome is an ongoing process that contributes to the development of pathological conditions in humans. However, the causal factors of this biological phenomenon in human cells are poorly studied. Here we analyzed mtDNA insertions in the nuclear genome of human l...

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Detalles Bibliográficos
Autores principales: Harutyunyan, Tigran, Al-Rikabi, Ahmed, Sargsyan, Anzhela, Hovhannisyan, Galina, Aroutiounian, Rouben, Liehr, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589397/
https://www.ncbi.nlm.nih.gov/pubmed/33080837
http://dx.doi.org/10.3390/ijms21207690