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First Identification of RNA-Binding Proteins That Regulate Alternative Exons in the Dystrophin Gene

The Duchenne muscular dystrophy (DMD) gene has a complex expression pattern regulated by multiple tissue-specific promoters and by alternative splicing (AS) of the resulting transcripts. Here, we used an RNAi-based approach coupled with DMD-targeted RNA-seq to identify RNA-binding proteins (RBPs) th...

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Detalles Bibliográficos
Autores principales: Miro, Julie, Bougé, Anne-Laure, Murauer, Eva, Beyne, Emmanuelle, Da Cunha, Dylan, Claustres, Mireille, Koenig, Michel, Tuffery-Giraud, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589424/
https://www.ncbi.nlm.nih.gov/pubmed/33096920
http://dx.doi.org/10.3390/ijms21207803