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Alpha-Synuclein in Alcohol Use Disorder, Connections with Parkinson’s Disease and Potential Therapeutic Role of 5’ Untranslated Region-Directed Small Molecules

Alpha-synuclein (α-Syn) is a 140-amino acid (aa) protein encoded by the Synuclein alpha SNCA gene. It is the synaptic protein associated with Parkinson’s disease (PD) and is the most highly expressed protein in the Lewy bodies associated with PD and other alpha synucleopathies, including Lewy body d...

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Detalles Bibliográficos
Autores principales: Cahill, Catherine M., Aleyadeh, Rozaleen, Gao, Jin, Wang, Changning, Rogers, Jack T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589448/
https://www.ncbi.nlm.nih.gov/pubmed/33096655
http://dx.doi.org/10.3390/biom10101465