MutSignatures: an R package for extraction and analysis of cancer mutational signatures

Cancer cells accumulate somatic mutations as result of DNA damage, inaccurate repair and other mechanisms. Different genetic instability processes result in characteristic non-random patterns of DNA mutations, also known as mutational signatures. We developed mutSignatures, an integrated R-based com...

Descripción completa

Detalles Bibliográficos
Autores principales: Fantini, Damiano, Vidimar, Vania, Yu, Yanni, Condello, Salvatore, Meeks, Joshua J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589488/
https://www.ncbi.nlm.nih.gov/pubmed/33106540
http://dx.doi.org/10.1038/s41598-020-75062-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589488/
https://www.ncbi.nlm.nih.gov/pubmed/33106540
http://dx.doi.org/10.1038/s41598-020-75062-0

Ejemplares similares