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Biomimetic Artificial Membrane Permeability Assay over Franz Cell Apparatus Using BCS Model Drugs

A major parameter controlling the extent and rate of oral drug absorption is permeability through the lipid bilayer of intestinal epithelial cells. Here, a biomimetic artificial membrane permeability assay (Franz–PAMPA Pampa) was validated using a Franz cells apparatus. Both high and low permeabilit...

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Detalles Bibliográficos
Autores principales: de Souza Teixeira, Leonardo, Vila Chagas, Tatiana, Alonso, Antonio, Gonzalez-Alvarez, Isabel, Bermejo, Marival, Polli, James, Rezende, Kênnia Rocha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589491/
https://www.ncbi.nlm.nih.gov/pubmed/33086670
http://dx.doi.org/10.3390/pharmaceutics12100988