CDDO-Me Distinctly Regulates Regional Specific Astroglial Responses to Status Epilepticus via ERK1/2-Nrf2, PTEN-PI3K-AKT and NFκB Signaling Pathways

2-Cyano-3,12-dioxo-oleana-1,9(11)-dien-28-oic acid methyl ester (CDDO-Me) is a triterpenoid analogue of oleanolic acid. CDDO-Me shows anti-inflammatory and neuroprotective effects. Furthermore, CDDO-Me has antioxidant properties, since it activates nuclear factor-erythroid 2-related factor 2 (Nrf2),...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Park, Hana, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589507/
https://www.ncbi.nlm.nih.gov/pubmed/33096818
http://dx.doi.org/10.3390/antiox9101026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589507/
https://www.ncbi.nlm.nih.gov/pubmed/33096818
http://dx.doi.org/10.3390/antiox9101026

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