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Modelling C9orf72-Related Amyotrophic Lateral Sclerosis in Zebrafish

A hexanucleotide repeat expansion within the C9orf72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and its discovery has revolutionized our understanding of this devastating disease. Model systems are a valuable tool for studying ALS pathobiology and potential therapie...

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Detalles Bibliográficos
Autores principales: Fortier, Gabrielle, Butti, Zoé, Patten, Shunmoogum A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589578/
https://www.ncbi.nlm.nih.gov/pubmed/33096681
http://dx.doi.org/10.3390/biomedicines8100440