GPR4 Knockout Improves the Neurotoxin-Induced, Caspase-Dependent Mitochondrial Apoptosis of the Dopaminergic Neuronal Cell

In Parkinson’s disease, mitochondrial oxidative stress-mediated apoptosis is a major cause of dopaminergic neuronal loss in the substantia nigra (SN). G protein-coupled receptor 4 (GPR4), previously recognised as an orphan G protein coupled-receptor (GPCR), has recently been claimed as a member of t...

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Detalles Bibliográficos
Autores principales: Haque, Md Ezazul, Akther, Mahbuba, Azam, Shofiul, Choi, Dong-Kug, Kim, In-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589616/
https://www.ncbi.nlm.nih.gov/pubmed/33053856
http://dx.doi.org/10.3390/ijms21207517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589616/
https://www.ncbi.nlm.nih.gov/pubmed/33053856
http://dx.doi.org/10.3390/ijms21207517

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