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Antiarrhythmic Effect of Ranolazine in Combination with Selective NCX-Inhibition in an Experimental Model of Atrial Fibrillation

The aim of this study was to investigate the effects of a combination of ranolazine with different selective inhibitors of the Na(+)/Ca(2+)-exchanger (NCX) in an established experimental model of atrial fibrillation (AF). Eighteen hearts of New Zealand white rabbits were retrogradely perfused. Atria...

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Detalles Bibliográficos
Autores principales: Wolfes, Julian, Ellermann, Christian, Broer, Niklas, Rath, Benjamin, Willy, Kevin, Leitz, Patrick Robert, Lange, Philipp Sebastian, Eckardt, Lars, Frommeyer, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589655/
https://www.ncbi.nlm.nih.gov/pubmed/33092020
http://dx.doi.org/10.3390/ph13100321