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Neurotrophic Properties of C-Terminal Domain of the Heavy Chain of Tetanus Toxin on Motor Neuron Disease

The carboxyl-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) exerts a neuroprotective effect in neurodegenerative diseases via the activation of signaling pathways related to neurotrophins, and also through inhibiting apoptotic cell death. Here, we demonstrate that Hc-TeTx preserves mo...

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Detalles Bibliográficos
Autores principales: Herrando-Grabulosa, Mireia, Casas, Caty, Talbot, Kevin, Aguilera, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589688/
https://www.ncbi.nlm.nih.gov/pubmed/33096857
http://dx.doi.org/10.3390/toxins12100666