Controlled Delivery of BET-PROTACs: In Vitro Evaluation of MZ1-Loaded Polymeric Antibody Conjugated Nanoparticles in Breast Cancer

Bromo and extraterminal domain (BET) inhibitors-PROteolysis TArgeting Chimera (BETi-PROTAC) is a new family of compounds that induce proteasomal degradation through the ubiquitination of the tagged to BET inhibitors Bromodomain proteins, BRD2 and BRD. The encapsulation and controlled release of BET-...

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Detalles Bibliográficos
Autores principales: Cimas, Francisco J., Niza, Enrique, Juan, Alberto, Noblejas-López, María del Mar, Bravo, Iván, Lara-Sanchez, Agustín, Alonso-Moreno, Carlos, Ocaña, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589709/
https://www.ncbi.nlm.nih.gov/pubmed/33086530
http://dx.doi.org/10.3390/pharmaceutics12100986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589709/
https://www.ncbi.nlm.nih.gov/pubmed/33086530
http://dx.doi.org/10.3390/pharmaceutics12100986

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