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Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling

The epidermal growth factor receptor (EGFR) signaling is important for normal development, such as vulval development in Caenorhabditis elegans, and hyperactivation of the EGFR is often associated with cancer development. Our previous report demonstrated the multivulva (Muv) phenotype, a tumor model...

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Detalles Bibliográficos
Autores principales: Choi, Junghwa, Sung, Jee Young, Lee, Saerom, Yoo, Jungyoen, Rongo, Christopher, Kim, Yong-Nyun, Shim, Jaegal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589727/
https://www.ncbi.nlm.nih.gov/pubmed/33092268
http://dx.doi.org/10.3390/ijms21207770