The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2

The human L-type amino acid transporters LAT1 and LAT2 mediate the transport of amino acids and amino acid derivatives across plasma membranes in a sodium-independent, obligatory antiport mode. In mammalian cells, LAT1 and LAT2 associate with the type-II membrane N-glycoprotein 4F2hc to form heterom...

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Detalles Bibliográficos
Autores principales: Kantipudi, Satish, Jeckelmann, Jean-Marc, Ucurum, Zöhre, Bosshart, Patrick D., Fotiadis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589757/
https://www.ncbi.nlm.nih.gov/pubmed/33066406
http://dx.doi.org/10.3390/ijms21207573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589757/
https://www.ncbi.nlm.nih.gov/pubmed/33066406
http://dx.doi.org/10.3390/ijms21207573

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