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Adeno-Associated Virus (AAV-DJ)—Cryo-EM Structure at 1.56 Å Resolution

Adeno-associated virus is the leading viral vector for gene therapy. AAV-DJ is a recombinant variant developed for tropism to the liver. The AAV-DJ structure has been determined to 1.56 Å resolution through cryo-electron microscopy (cryo-EM). Only apoferritin is reported in preprints at 1.6 Å or hig...

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Detalles Bibliográficos
Autores principales: Xie, Qing, Yoshioka, Craig K., Chapman, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589773/
https://www.ncbi.nlm.nih.gov/pubmed/33092282
http://dx.doi.org/10.3390/v12101194