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How HIV-1 Integrase Associates with Human Mitochondrial Lysyl-tRNA Synthetase

Replication of human immunodeficiency virus type 1 (HIV-1) requires the packaging of tRNA(Lys,3) from the host cell into the new viral particles. The GagPol viral polyprotein precursor associates with mitochondrial lysyl-tRNA synthetase (mLysRS) in a complex with tRNA(Lys), an essential step to init...

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Detalles Bibliográficos
Autores principales: Phongsavanh, Xaysongkhame, Al-Qatabi, Noha, Shaban, Mohammed Samer, Khoder-Agha, Fawzi, El Asri, Merwan, Comisso, Martine, Guérois, Raphaël, Mirande, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589778/
https://www.ncbi.nlm.nih.gov/pubmed/33096929
http://dx.doi.org/10.3390/v12101202