Toward Drug-Like Multispecific Antibodies by Design

The success of antibody therapeutics is strongly influenced by their multifunctional nature that couples antigen recognition mediated by their variable regions with effector functions and half-life extension mediated by a subset of their constant regions. Nevertheless, the monospecific IgG format is...

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Detalles Bibliográficos
Autores principales: Sawant, Manali S., Streu, Craig N., Wu, Lina, Tessier, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589779/
https://www.ncbi.nlm.nih.gov/pubmed/33053650
http://dx.doi.org/10.3390/ijms21207496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589779/
https://www.ncbi.nlm.nih.gov/pubmed/33053650
http://dx.doi.org/10.3390/ijms21207496

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