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Novel Sulfonamide-Based Analogs of Metformin Exert Promising Anti-Coagulant Effects without Compromising Glucose-Lowering Activity

Metformin, one of the most frequently prescribed oral anti-diabetic drugs, is characterized by multidirectional activity, including lipid lowering, cardio-protective and anti-inflammatory properties. This study presents synthesis and stability studies of 10 novel sulfonamide-based derivatives of met...

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Detalles Bibliográficos
Autores principales: Markowicz-Piasecka, Magdalena, Sadkowska, Adrianna, Sikora, Joanna, Broncel, Marlena, Huttunen, Kristiina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589829/
https://www.ncbi.nlm.nih.gov/pubmed/33096688
http://dx.doi.org/10.3390/ph13100323