Trastuzumab Modified Barium Ferrite Magnetic Nanoparticles Labeled with Radium-223: A New Potential Radiobioconjugate for Alpha Radioimmunotherapy

Barium ferrite nanoparticles (BaFeNPs) were investigated as vehicles for (223)Ra radionuclide in targeted α-therapy. BaFe nanoparticles were labeled using a hydrothermal Ba(2+) cations replacement by (223)Ra with yield reaching 61.3 ± 1.8%. Radiolabeled nanoparticles were functionalized with 3-phosp...

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Detalles Bibliográficos
Autores principales: Gawęda, Weronika, Pruszyński, Marek, Cędrowska, Edyta, Rodak, Magdalena, Majkowska-Pilip, Agnieszka, Gaweł, Damian, Bruchertseifer, Frank, Morgenstern, Alfred, Bilewicz, Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589850/
https://www.ncbi.nlm.nih.gov/pubmed/33092037
http://dx.doi.org/10.3390/nano10102067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589850/
https://www.ncbi.nlm.nih.gov/pubmed/33092037
http://dx.doi.org/10.3390/nano10102067

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