SOX9 Knockout Induces Polyploidy and Changes Sensitivity to Tumor Treatment Strategies in a Chondrosarcoma Cell Line

As most chemotherapeutic drugs are ineffective in the treatment of chondrosarcoma, we studied the expression pattern and function of SOX9, the master transcription factor for chondrogenesis, in chondrosarcoma, to understand the basic molecular principles needed for engineering new targeted therapies...

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Detalles Bibliográficos
Autores principales: Stöckl, Sabine, Lindner, Georg, Li, Shushan, Schuster, Philipp, Haferkamp, Sebastian, Wagner, Ferdinand, Prodinger, Peter M., Multhoff, Gabriele, Boxberg, Melanie, Hillmann, Axel, Bauer, Richard J., Grässel, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589851/
https://www.ncbi.nlm.nih.gov/pubmed/33076370
http://dx.doi.org/10.3390/ijms21207627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589851/
https://www.ncbi.nlm.nih.gov/pubmed/33076370
http://dx.doi.org/10.3390/ijms21207627

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