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Atorvastatin Augments Gemcitabine-Mediated Anti-Cancer Effects by Inhibiting Yes-Associated Protein in Human Cholangiocarcinoma Cells

Cholangiocarcinoma (CCA) is associated with high mortality rates because of its resistance to conventional gemcitabine-based chemotherapy. Hydroxy-methyl-glutaryl-coenzyme A reductase inhibitors (statins) reportedly exert anti-cancer effects in CCA and lower the risk of CCA; however, the underlying...

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Detalles Bibliográficos
Autores principales: Kitagawa, Koh, Moriya, Kei, Kaji, Kosuke, Saikawa, Soichiro, Sato, Shinya, Nishimura, Norihisa, Namisaki, Tadashi, Akahane, Takemi, Mitoro, Akira, Yoshiji, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589854/
https://www.ncbi.nlm.nih.gov/pubmed/33066548
http://dx.doi.org/10.3390/ijms21207588